Advantage II Large Dog Flea Treatment | 21-55 lbs | 6-Month

Reliable flea control for medium to large dogs. Advantage II Large Dog Flea Treatment provides comprehensive, vet-recommended flea protection for dogs weighing 21–55 lbs — killing fleas, larvae, and eggs to break the flea lifecycle and eliminate infestations with monthly topical applications.

Advantage II's dual-action formula kills adult fleas on contact within 12 hours through Imidacloprid, while Pyriproxyfen kills flea larvae and prevents eggs from hatching — attacking the flea lifecycle at every stage simultaneously. Monthly application provides 30 days of waterproof protection per dose. The treatment begins working almost immediately, providing rapid relief from fleas and their associated irritation. Six applications in each package provide your medium or large dog with a full 6 months of continuous flea protection — the most economical way to keep your pet flea-free year-round.

Active Ingredients: Imidacloprid + Pyriproxyfen  |  Dog Size: 21–55 lbs
Supply: 6-Month (6 doses)  |  Application: Monthly topical

Frequently Asked Questions

When will Advantage II start killing fleas?

Advantage II starts killing fleas within 12 hours of application and eliminates re-infesting fleas from the environment within 2 hours. The vast majority of fleas are killed within 1 hour of contact with your treated dog.

Is this 100% authentic?

Yes — all Hamxi products are 100% authentic, sourced from authorized distributors.

✔ 100% Authentic  |  ✔ Free Shipping on $50+  |  ✔ 30-Day Hassle-Free Returns

- No EU import duties.
- Ships within 1-2 business days.
- Ships in our fully recyclable and biodegradable signature boxes.

Regularcare. Use a slightly damp, soft and lint-free cloth for regular dust removal. Always clean in the direction of the grain.